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Signagen/AAV-Syn-iCre (AAV Serotype 5)/SL101443/>30 µL (Std Pack)
ProductCategory: Pre-maderecombinantAAV;AAV-Synapsin-iCre;AAV-Syn-iCre;AAV5-Synapsin-iCre;AAV5-Syn-iCre
Description:
CrerecombinaseisatypeItopoisomerasefrombacteriophageP1thatcatalyzesthesite-specificrecombinationofDNAbetweenloxPsites. Crerecombinaseisusedasatooltogeneticallymodifygenes,suchastodeleteasegmentofDNAflankedbyLoxPsitesincellsorexperimentalanimals. ByoptimizingthemammaliancodonusageforCrerecombinase,Creexpressionisimprovedinthemammaliancells.Thiscodon-improvedCre(knownasiCre)transgeneshowslowerCpGcontentfromtheprokaryoticcodingsequence,thusreducingthechancesofepigeneticsilencinginmammals.
AAV5-Syn-iCreisapre-packagedrAAVinSEROtype5(withcapsidfromAAVserotype5and2xITRfromAAVserotype2)whichover-expressesiCrerecombinaseunderhumansynapsinpromoterforexclusiveneuronalexpression.ThisproductusedintheCre-loxsystemasagenetictooltogeneratesite-specificrecombinationofDNAbetweenloxPsitesinculturedcellsandanimalexperiments. Readytouseformat.
Titer: >1x1013 VG/mL
Size: > 30 µL(StdPack)
StorageBuffer: PBS
InfectionProtocol: 
VectorMap: 
